Dr. Lukas A. Basedow

Postdoctoral Researcher



Dept. of Psychology - Clinical Psychology and Psychotherapy I

Phillips Universität Marburg



Attenuated psychotic symptoms, substance use and self-reported PTSD in adolescence


Journal article


Lukas A. Basedow, Melina F. Wiedmann, Sören Kuitunen-Paul, Veit Roessner, Yulia Golub
European Journal of Psychotraumatology, vol. 14, 2023 Nov, p. 2193327


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APA   Click to copy
Basedow, L. A., Wiedmann, M. F., Kuitunen-Paul, S., Roessner, V., & Golub, Y. (2023). Attenuated psychotic symptoms, substance use and self-reported {PTSD} in adolescence. European Journal of Psychotraumatology, 14, 2193327. https://doi.org/10.1080/20008066.2023.2193327


Chicago/Turabian   Click to copy
Basedow, Lukas A., Melina F. Wiedmann, Sören Kuitunen-Paul, Veit Roessner, and Yulia Golub. “Attenuated Psychotic Symptoms, Substance Use and Self-Reported {PTSD} in Adolescence.” European Journal of Psychotraumatology 14 (November 2023): 2193327.


MLA   Click to copy
Basedow, Lukas A., et al. “Attenuated Psychotic Symptoms, Substance Use and Self-Reported {PTSD} in Adolescence.” European Journal of Psychotraumatology, vol. 14, Nov. 2023, p. 2193327, doi:10.1080/20008066.2023.2193327.


BibTeX   Click to copy

@article{basedow2023a,
  title = {Attenuated psychotic symptoms, substance use and self-reported {PTSD} in adolescence},
  year = {2023},
  month = nov,
  journal = {European Journal of Psychotraumatology},
  pages = {2193327},
  volume = {14},
  doi = {10.1080/20008066.2023.2193327},
  author = {Basedow, Lukas A. and Wiedmann, Melina F. and Kuitunen-Paul, Sören and Roessner, Veit and Golub, Yulia},
  month_numeric = {11}
}

ABSTRACT
Background: The occurrence of attenuated psychotic symptoms (APS) is a major concern in populations with substance use disorders (SUDs). However, APS also frequently develop in the course of Post-Traumatic Stress Disorder (PTSD). This study explores how the prevalence of APS differs between adolescent patients with only SUD, SUD with a history of traumatic experiences (TEs), and with SUD and self-reported PTSD.

Methods: We recruited n = 120 treatment-seeking adolescents at a German outpatient clinic for adolescents with SUD. All participants filled out questionnaires assessing APS (PQ-16, YSR schizoid scale), trauma history, PTSD symptoms (both UCLA PTSD Index), and SUD severity (DUDIT) next to an extensive substance use interview. We performed a multivariate analysis of co-variance with the four PQ-16 scales and the YSR scale as outcomes and PTSD status as predictor. Additionally, we performed five linear regressions predicting each PQ-16 score and YSR score based on tobacco, alcohol, cannabis, ecstasy, amphetamine, and methamphetamine use.

Results: Participants with co-occurring SUD and self-reported PTSD showed significantly higher APS prevalence rates (PQ-16 score, p = .00002), more disturbed thought content (p = .000004), more perceptual disturbances (p = .002), more negative symptoms (p = .004) and more thought problems (p = .001) compared to adolescents with SUD and a history of trauma and adolescents with only SUD. Past-year substance use was not predictive for APS prevalence (F(75) = 0.42; p = .86; R2 = .04).

Conclusion: Our data suggests that the occurrence of APS in adolescents with SUD is better explained by co-occurring self-reported PTSD than by substance use frequency or substance class. This finding might indicate that APS might be reduced through treating PTSD or focusing on TEs in SUD therapy.



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